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Master Thread Dance Your Cares Away/Fraggle/Law Abiding Citizens

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imprimis

Legendary
Founder
Joined
Jan 8, 2021
Messages
11,197
For guys do not sit in the shitter with your cell phone - he said this is the worst thing you can do.
Apparently, the cell phone has replaced the newspaper for shitter sitting.

Had my first and only one running up and down the hills at Camp Pendleton for 5 days bivouac. Pain In The Ass for sure. Then three more days after surgery when the Lidocaine wore off.
 

Goldhedge

Legendary
Joined
Mar 24, 2023
Messages
9,261

GROK: can nicotine cure Glioblastoma

25 web pages
Nicotine does not cure glioblastoma. Research suggests that nicotine might have complex effects on cancer cells, including those of glioblastoma, but these effects are generally not beneficial in terms of curing the disease. Here are some key points based on available studies:
  • Proliferation and Resistance: Nicotine has been shown to enhance proliferation, migration, and radioresistance of human malignant glioma cells by activating pathways like EGFR (Epidermal Growth Factor Receptor), AKT, and ERK. This could potentially worsen the prognosis rather than improve it.
    https://pubmed.ncbi.nlm.nih.gov/22614999/
  • Impact on Treatment: Some studies indicate that nicotine might contribute to resistance against chemoradiotherapy, suggesting a negative impact on the effectiveness of standard treatments for glioblastoma.
    https://pubmed.ncbi.nlm.nih.gov/31092064/
  • Metastasis Concerns: While nicotine itself is not carcinogenic, it has been associated with promoting the spread (metastasis) of cancer cells, notably in lung cancer to the brain, which could imply a similar risk in glioblastoma due to its influence on the tumor microenvironment.
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7398164/
  • Experimental Findings: In some experimental settings, nicotine has been linked to increased proliferation of glioblastoma cells, but this does not translate to a curative effect. Instead, it might exacerbate the condition by promoting tumor growth or survival.
    https://www.sciencedirect.com/science/article/abs/pii/S1043661820316443
  • Public Perception vs. Scientific Evidence: Posts on social media platforms might claim nicotine's benefits in fighting brain tumors, but these are not supported by peer-reviewed scientific evidence and can be misleading.

To summarize, while nicotine has various biological effects, none of the current scientific evidence supports it as a cure for glioblastoma. On the contrary, it might have detrimental effects on cancer progression and treatment efficacy. Treatment for glioblastoma involves surgical resection, radiation, and chemotherapy, and patients should consult with healthcare professionals for guidance based on established medical protocols.
 

Cletusnow

Made the run from Texarkana to Atlanta
Founder
Joined
Jan 8, 2021
Messages
3,716
Man, I had the surgery about 5 years ago. Worse pain I have ever felt in my life. And, when you can finally shit after a few days you will honestly beg our Lord and savior to bring you home.
I got a bleeding one right now. Guess I’m heading to the ass doctor.
 

Zgdaf

Elite
Founder
Joined
Jan 9, 2021
Messages
1,705
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