"So why gene therapies didn't make it to market in
over 30 years of research? The reason why they never made it to market previously is because they have the tendency to cause lethal cancers, mostly leukemia, sometimes lymphomas, through integrating into host DNA, through a process called insertional mutagenesis in places where they should not be.
"They also cause lethal autoimmune reactions. There was the risk of an inadvertent gene transfer to the progeny if the gene therapy made it to the testes and ovaries, And this risk was seen as being so substantial that they actually sterilized the first recipients of gene therapies. In short, the risk was only worth a reward for otherwise lethal disease. And you can read about this in Nancy M.P. King's Accident and Desire: Inadvertent Germline Effects in Clinical Research.
"So lipid nanoparticles, the delivery system. This delivery system coats the DNA and RNA that would otherwise be attacked by your body and degrade it. It transverses the outer cell membrane and also transverses the nuclear membrane where it can drop the payload. Lipid and PEG toxicity is intrinsically unsafe. So the LNPs themselves, are toxic. DSPC [1,2-Distearoyl-sn-glycero-3-phosphocholine, a type of phospholipid] is toxic to reproduction. It's toxic to fetuses and embryos. It's toxic to the liver, and it's a confirmed animal carcinogen, and it is part of the formulation of the lipid nanoparticles. Seventy-two percent (72%) of people are estimated to have antibodies to polyethylene glycol. Some of these antibody reactions are fatal in other formulations such as the cancer drug Doxyl.
"The genetic vaccines don't stay at the injection site.
So both Moderna and Pfizer studies showed that these genetic vaccines go all over the body, preferentially to the ovaries, but also the testes, the bone marrow, the brain, the skin, um, the liver, the blood to all the organs, essentially. And that is not what people were told. People were told that they would stay mainly at the injection site.


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